An Online Responder can be installed on any computer running Windows Server 2008 R2 Enterprise, Windows Server 2008 R2 Datacenter, Windows Server 2008 Enterprise, or Windows Server 2008 Datacenterso whilst a CA won't stop you / warn you about enabling OSCP links in the AIA section, it will only work if the specified http:// link defined in the AIA section is hosted on a ENT or DC version of server 2008 R2, and if you enable OSCP via the link then various systems will take that as preferred then fail if the responder service is not running.
ref https://technet.microsoft.com/en-us/library/cc725937%28v=ws.11%29.aspx?f=255&MSPPError=-2147217396